The Impact of COVID-19 on Lung Cancer Incidence in England: Analysis of the National Lung Cancer Audit 2019 and 2020 Rapid Cancer Registration Datasets.

BACKGROUND: The COVID-19 pandemic has caused significant disruption to health-care services and delivery worldwide. The impact of the pandemic and associated national lockdowns on lung cancer incidence in England have yet to be assessed. RESEARCH QUESTION: What was the impact of the first year of the COVID-19 pandemic on the incidence and presentation of lung cancer in England? STUDY DESIGN AND METHODS: In this retrospective observational study, incidence rates for lung cancer were calculated from The National Lung Cancer Audit Rapid Cancer Registration Datasets for 2019 and 2020, using midyear population estimates from the Office of National Statistics as the denominators. Rates were compared using Poisson regression according to time points related to national lockdowns in 2020. RESULTS: Sixty-four thousand four hundred fifty-seven patients received a diagnosis of lung cancer across 2019 (n = 33,088) and 2020 (n = 31,369). During the first national lockdown, a 26% reduction in lung cancer incidence was observed compared with the equivalent calendar period of 2019 (adjusted incidence rate ratio [IRR], 0.74; 95% CI, 0.71-0.78). This included a 23% reduction in non-small cell lung cancer (adjusted IRR, 0.77; 95% CI, 0.74-0.81) and a 45% reduction in small cell lung cancer (adjusted IRR, 0.55; 95% CI, 0.46-0.65) incidence. Thereafter, incidence rates almost recovered to baseline, without overcompensation (adjusted IRR, 0.96; 95% CI, 0.94-0.98). INTERPRETATION: The incidence rates of lung cancer in England fell significantly by 26% during the first national lockdown in 2020 and did not compensate later in the year.

Supply chain transparency: A bibliometric review and research agenda

ABSTRACT Many organizations are confronted with the challenge of improving supply chain transparency not only to meet regulatory requirements, but also to optimize operations, guarantee the quality of outputs, and ensure the sustainability of processes. As this topic has garnered significant interest across a wide range of academic disciplines, there is a need to synthesize and categorize these diverse contributions to inspire future investigations of emerging or under-researched substantive areas. This article addresses this need by reviewing existing research on supply chain transparency and offers an integrated understanding of this growing literature. By analyzing a sample of over 300 peer-reviewed articles through bibliometric and automated text mining methods, we identify six distinct clusters that represent substantive literature subdomains: transparency technologies, knowledge integration, governance, sustainability, traceability, and resilience. Building on these structured analyses, we develop a literature framework to comprehensively organize insights from these clusters and illustrate the conceptual relationships between transparency management systems, transparency vehicles, and transparency outcomes. By providing a holistic examination of how supply chain transparency is enabled, our framework aids researchers’ future studies and guides practitioners’ strategies to identify, diagnose, and address modern challenges that face supply chains (e.g., COVID-19 pandemic, workplace exploitation, increased third-party scrutiny).